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Nanowerk is spotlighting research by Argonne National Laboratory scientists to develop bioconjugated nanoparticles that seek out brain tumor cells while avoiding attack on healthy tissue. Although various nanoparticles tend to passively gather in larger numbers in tumor cells du...
Researchers from McGill University and Argonne National Laboratory have published a paper in Nanoscale discussing the potential use of quantum nanodots, or nano sized particles of semiconductor material, to produce reactive oxygen species for killing cancer cells using photodyn...
Among Dr. Soman's first experiments was to see how melittin interacted with the nanoparticles. He found that not only did it attach quickly to the outer, lipid layer of the nanoparticles, but that the attachment was stable, suggesting that the nanoparticle-melittin combination, or nan...
An international team of collaborators from a number of academic institutions and a couple pharmaceutical firms has been working with researchers at the National Institute of Standards and Technology (NIST) to study how special sugar coated iron oxide nanoparticles interact with e...
They mix the chemical to be encapsulated with a small amount of carbon nanotubes and the precursors for making nylon, while continuously stirring. The stirring causes the nylon to form spheres that capture the nanotubes and the reactant. By varying the stir rate, the Berkeley chemists ca...
The researchers embedded nanoscale particles of PNIPAM-based gels in an ethyl cellulose membrane so that clumps of the particles spanned the width of the membrane. They also entrapped magnetite nanoparticles within the membrane matrix. If the membrane is exposed to an oscillating mag...
Carbon nanotubes have been shown to be promising as imaging agents for spotting tumors, inflammation, and other processes inside the body. Not only due to their novelty, but also because of their potential toxicity, these particles have not been fully realized for medical application...
A research team from Norfolk State University and Purdue has built on the work of Mark Stockman of Georgia State and David Bergman of Tel Aviv University to create a laser on the nanoscale. Though light can't be focused past around half its wavelengths, plasmons (quantum of plasma oscilla...
Chemistry professor Michael Sailor and a team including National Science Foundation supported researchers at the University of California, San Diego, report developing the first nanoscale "quantum dot" particle that glows brightly enough to allow physicians to examine internal...
So far most cancer research has combined nanoparticles either with chemotherapy that kills cancer cells, or therapy seeking to disrupt the genetic activity of a cancerous cell. This is the first time that nanoparticles have been combined with a therapy that physically stops cancer's s...
The promise of DNA nanomachines that can change shape due to specific triggers, and in such a way create complicated systems, is not a new notion. In the latest edition of Nature Nanotechnology, Indian scientists are reporting the development of an interesting DNA pH sensor, a DNA nanoma...
The Brookhaven team has previously used DNA, the molecule that carries life’s genetic code, to link up nanoparticles in various arrangements, including 3-D nano-crystals. The idea is that nanoparticles coated with complementary strands of DNA — segments of genetic code sequence tha...
The novel probes were tested in cultured cancer cells. Irudayaraj said the next step would be to run a series of tests in mice models to determine the dose and stability of the probes. Press release: Nanoscopic probes can track down and attack cancer cells
Image: This colorized atomic force microscope image shows a carbon nanotube that is two micrometers long and one nanometer wide. It is covered with light-sensing molecules that respond to visible light and that are not visible in this image. Light-sensitive carbon nanotubes could be us...
The paper was first-authored by Jesper Matthiesen who is now at Pacific Northwest National Laboratory. The team, which included members of iNANO's Scanning Probe Microscopy Group, led by Flemming Besenbacher, and Theoretical Surface Science Group, led by Bjørk Hammer, specificall...
Philips’ Magnetic Particle Imaging uses the magnetic properties of injected iron-oxide nanoparticles to measure the nanoparticle concentration in the blood. Because the human body contains no naturally occurring magnetic materials visible to MPI, there is no background signal. Af...
With hollow gold nanospheres inside melanoma cells, photothermal ablation destroyed tumors in mice with a laser light dose that was 12 percent of the dose required when the nanospheres aren't applied, Li [Chun Li, Ph.D., professor in M. D. Anderson's Department of Experimental Diagnosti...
The next step for engineers will be to work with orthopedic surgeons and other colleagues at the UC San Diego School of Medicine to study ways to translate this breakthrough research to clinical application, said Shu Chien, a UC San Diego bioengineering professor and director of the uni...
With the two types of antibody-linked nanoparticles in hand, the investigators conducted a series of experiments to determine whether these nanoscale constructs would target tumors and whether tumor cells would take up take the antibody-nanoparticle combos. Indeed, targeted nano...
Using the sensors, researchers can monitor living cells over an extended period of time. The sensor can pinpoint the exact location of molecules inside cells, and for one agent, hydrogen peroxide, it can detect a single molecule. Nanotubes sniff out cancer agents in living cells ...
Dr. Hossam Haick and colleagues from the Israel Institute of Technology have published an article in Nano Letters describing their technology for detecting lung cancer markers in human breath. Image: Lung cancer cells. Wellcome Images.
TSOM has also been theoretically evaluated in another quality control application. Medical researchers are studying the use of gold nanoparticles to deliver advanced pharmaceuticals to specific locations within the human body. Perfect size will be critical. To address this applicat...
From MIT Tech Review: Electrodes are placed in a water-based solution of carbon nanotubes; when a small voltage is applied to sites on the electrodes, carbon nanotubes localize there and can be fixed. Joseph Pancrazio, a neuroscientist at the National Institute of Neurological Disord...
A vial of anti-cancer nano ships glows red under a black light. The particles glow red because they contain fluorescent "quantum dot" nanoparticles. Side: The nanometer-sized cargo ships look individually like a chocolate-covered nut cluster, in which a biocompatible lipid forms the...
At the Dean A. McGee Eye Institute in Oklahoma City, Oklahoma special nanoparticles are being studied as a potential treatment for retinal disease. Nanoceria, a type of nanoparticle made out of cerium oxide molecules has some interesting properties, including the ability to scavenge f...
While previous research has looked at how molecular devices rotate in flowing gases, Král and his group are the first to look at molecular propeller pumping of liquids, notably water and oils. Petr Král's Design and Modeling of Nanoscale Systems Group
Throughout this work, the biggest challenge was to synthesize size-controllable nanoparticles coated with organic molecules designed to react with specific protein sites. Hu explains the steps: "First, we design the specific interactions between gold nanoparticles and the prote...
The latest most excellent Nanowerk Spotlight by Michael Berger is about the latest efforts of scientists to figure out how self-repairing nanomaterials will be constructed in the future. One can only imagine the immense implications for clinical medicine that such materials will hav...
Led by CMU chemist Marcel Bruchez and Steven Toms, director of neurosurgery at the Geisinger Clinic, in Danville, PA, the researchers took crisp fluorescent images of brain tumors, called gliomas, in rats. The rats had been injected with nanoparticles that emit infrared light when the...
To overcome these problems, drug delivery systems using pegylated polymers, liposomal particles or albumin-based nanoparticles have been developed. Press release: Researchers at UCLA Develop New Nanomaterials to Deliver Anticancer Drugs to Kill Cancer Cells ...
To achieve this detailed study, the team of scientists (including physicists, biologists and chemists) developed a slow technique which enabled the coating with silica of nanotubes of biological molecules forming in water. They were surprised to observe that the silica deposit favo...
Even on nano scale, size matters. University of Cincinnati researchers are reporting "growing" nanotube arrays up to 18 mm in length, a development that might have some serious implications for the development of electronics for clinical/diagnostic applications: Carbon nanotubes...
In an effort that might affect the future of nanomedicine, scientists at UC Berkley have developed a novel "hyperlens" which they claim brings them a step closer to nanoscale optical imaging. Here's a scoop from UC Berkeley: Propagating waves can travel far and be collected by an optical...
The researchers attributed the improved sensibility to various factors related to the application of platinum to the multi-walled nanotubes. Most importantly, the platinum nanoparticles created a larger electro-active surface area on the carbon nanotubes. Xie said the larger surf...